A Medicinal Herb Scutellaria lateriflora Inhibits PrP Replication in vitro and Delays the Onset of Prion Disease in Mice

Transmissible spongiform encephalopathies (TSE) are characterized by the misfolding of the host encoded prion protein (PrP(C)) into a pathogenic isoform (PrP(Sc)) which leads to the accumulation of β-sheet-rich fibrils and subsequent loss of neurons and synaptic functions. Although many compounds ha...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Eiden, Martin, Leidel, Fabienne, Strohmeier, Barbara, Fast, Christine, Groschup, Martin H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Research Foundation 2012
Materias:
Psychiatry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281244/
https://ncbi.nlm.nih.gov/pubmed/22363300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2012.00009
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares