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Anti-PrP antibodies block PrP(Sc) replication in prion-infected cell cultures by accelerating PrP(C) degradation
The usage of anti-PrP antibodies represent one of the most promising strategy for the treatment of prion diseases. In the present study, we screened various anti-PrP antibodies, with the aim to identify those that will block PrP(Sc) replication in prion infected cell culture. Two antibodies, SAF34 r...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2063508/ https://ncbi.nlm.nih.gov/pubmed/15056288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2004.02356.x |
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