Anti-PrP antibodies block PrP(Sc) replication in prion-infected cell cultures by accelerating PrP(C) degradation

The usage of anti-PrP antibodies represent one of the most promising strategy for the treatment of prion diseases. In the present study, we screened various anti-PrP antibodies, with the aim to identify those that will block PrP(Sc) replication in prion infected cell culture. Two antibodies, SAF34 r...

Full description

Saved in:
Bibliographic Details
Main Authors: Perrier, Véronique, Solassol, Jérôme, Crozet, Carole, Frobert, Yveline, Mourton-Gilles, Chantal, Grassi, Jacques, Lehmann, Sylvain
Format: Artigo
Language:Inglês
Published: Blackwell Science 2004
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063508/
https://ncbi.nlm.nih.gov/pubmed/15056288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2004.02356.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items