Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly

Human immunodeficiency virus type-1 (HIV-1) encodes a polypeptide called Gag that is able to form virus-like particles in vitro in the absence of any cellular or viral constituents. During the late phase of the HIV-1 infection, Gag polyproteins are transported to the plasma membrane (PM) for assembl...

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Bibliographic Details
Main Authors: Ghanam, Ruba H., Samal, Alexandra B., Fernandez, Timothy F., Saad, Jamil S.
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2012
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281212/
https://ncbi.nlm.nih.gov/pubmed/22363329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2012.00055
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