Structural basis for targeting avian sarcoma virus Gag polyprotein to the plasma membrane for virus assembly

For most retroviruses, including HIV-1, binding of the Gag polyprotein to the plasma membrane (PM) is mediated by interactions between Gag's N-terminal myristoylated matrix (MA) domain and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) in the PM. The Gag protein of avian sarcoma virus (ASV...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Vlach, Jiri, Eastep, Gunnar N., Ghanam, Ruba H., Watanabe, Susan M., Carter, Carol A., Saad, Jamil S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295720/
https://ncbi.nlm.nih.gov/pubmed/30309983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003944
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