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Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly

During the late phase of HIV type 1 (HIV-1) replication, newly synthesized retroviral Gag proteins are targeted to the plasma membrane of most hematopoietic cell types, where they colocalize at lipid rafts and assemble into immature virions. Membrane binding is mediated by the matrix (MA) domain of...

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Detalhes bibliográficos
Main Authors: Saad, Jamil S., Miller, Jaime, Tai, Janet, Kim, Andrew, Ghanam, Ruba H., Summers, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544092/
https://ncbi.nlm.nih.gov/pubmed/16840558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602818103
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