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Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms
Dioxins are known to cause several human cancers through activation of the aryl hydrocarbon receptor (AhR). Harmaline and harmalol are β-carboline compounds present in several medicinal plants such as Peganum harmala. We have previously demonstrated the ability of Peganum harmala extract to inhibit...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281145/ https://ncbi.nlm.nih.gov/pubmed/22037238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2011.10.052 |
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