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Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms

Dioxins are known to cause several human cancers through activation of the aryl hydrocarbon receptor (AhR). Harmaline and harmalol are β-carboline compounds present in several medicinal plants such as Peganum harmala. We have previously demonstrated the ability of Peganum harmala extract to inhibit...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: El Gendy, Mohamed A.M., Soshilov, Anatoly A., Denison, Michael S., El-Kadi, Ayman O.S.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281145/
https://ncbi.nlm.nih.gov/pubmed/22037238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2011.10.052
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