The Effects of Low Levels of Dystrophin on Mouse Muscle Function and Pathology

Duchenne muscular dystrophy (DMD) is a severe progressive muscular disorder caused by reading frame disrupting mutations in the DMD gene, preventing the synthesis of functional dystrophin. As dystrophin provides muscle fiber stability during contractions, dystrophin negative fibers are prone to exer...

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Main Authors: van Putten, Maaike, Hulsker, Margriet, Nadarajah, Vishna Devi, van Heiningen, Sandra H., van Huizen, Ella, van Iterson, Maarten, Admiraal, Peter, Messemaker, Tobias, den Dunnen, Johan T., 't Hoen, Peter A. C., Aartsma-Rus, Annemieke
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281102/
https://ncbi.nlm.nih.gov/pubmed/22359642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031937
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