The Orphan Nuclear Receptor LRH-1 and ERα Activate GREB1 Expression to Induce Breast Cancer Cell Proliferation

BACKGROUND: Liver Receptor Homolog 1 (LRH-1, NR5A2) is an orphan nuclear receptor that is over-expressed in cancers in tissues such as the breast, colon and pancreas. LRH-1 plays important roles in embryonic development, steroidogenesis and cholesterol homeostasis. In tumor cells, LRH-1 induces prol...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chand, Ashwini L., Wijayakumara, Dhilushi D., Knower, Kevin C., Herridge, Kerrie A., Howard, Tamara L., Lazarus, Kyren A., Clyne, Colin D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281101/
https://ncbi.nlm.nih.gov/pubmed/22359603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031593
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados