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Aromatase expression is increased in BRCA1 mutation carriers

BACKGROUND: Until recently, the molecular mechanisms explaining increased incidence of ovarian and breast cancers in carriers of BRCA1 gene mutations had not been clearly understood. Of significance is the finding that BRCA1 negatively regulates aromatase expression in vitro. Our objective was to ch...

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Bibliografische gegevens
Hoofdauteurs: Chand, Ashwini L, Simpson, Evan R, Clyne, Colin D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689243/
https://ncbi.nlm.nih.gov/pubmed/19445691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-148
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