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Aromatase expression is increased in BRCA1 mutation carriers
BACKGROUND: Until recently, the molecular mechanisms explaining increased incidence of ovarian and breast cancers in carriers of BRCA1 gene mutations had not been clearly understood. Of significance is the finding that BRCA1 negatively regulates aromatase expression in vitro. Our objective was to ch...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2689243/ https://ncbi.nlm.nih.gov/pubmed/19445691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-148 |
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