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The Role of Conserved Waters in Conformational Transitions of Q61H K-ras
To investigate the stability and functional role of long-residence water molecules in the Q61H variant of the signaling protein K-ras, we analyzed all available Ras crystal structures and conformers derived from a series of independent explicit solvent molecular dynamics (MD) simulations totaling 1....
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3280954/ https://ncbi.nlm.nih.gov/pubmed/22359497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002394 |
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