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Acid-Triggered Transformation of Diortho Ester Phosphocholine Liposome

[Image: see text] The use of pH-sensitive liposomes for acid-triggered site specific drug delivery is one of the more promising approaches to improve the therapeutic index of drugs. Here, we report the synthesis, assembly, and hydrolysis of the first ortho ester phosphocholine (OEPC). The acid hydro...

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Detaylı Bibliyografya
Asıl Yazarlar: Huang, Zhaohua, Guo, Xin, Li, Weijun, MacKay, J. Andrew, Szoka, Francis C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280609/
https://ncbi.nlm.nih.gov/pubmed/16390121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja057024w
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