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All-trans retinoic acid potentiates the antibody response in mice to a lipopeptide antigen adjuvanted with liposomal lipid A

Retinoic acid (RA), the bioactive metabolite of retinol, is essential for robust humoral immunity in animals and humans. Recent interest in RA as a vaccine adjuvant has been encouraged by reports demonstrating cooperative enhancement of antibody responses to tetanus toxin in rodents by all-trans RA...

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Main Authors: Watson, Douglas S., Huang, Zhaohua, Szoka, Francis C.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784135/
https://ncbi.nlm.nih.gov/pubmed/19597529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2009.48
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