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Influence of multivalent nitrilotriacetic acid lipid-ligand affinity on the circulation half-life in mice of a liposome-attached his(6)-protein

Metal chelation-ligand interactions, such as occur between nitrilotriacetic acid (NTA)-nickel and multihistidines, enable the non-covalent attachment of histidine-modified proteins to liposomes and other particles. We compared three lipids: a mono-NTA lipid (circa 10 uM affinity) and two tris-NTA li...

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Bibliografiset tiedot
Päätekijät: Platt, Virginia, Huang, Zhaohua, Cao, Limin, Tiffany, Matthew, Riviere, Kareen, Szoka, Francis C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874083/
https://ncbi.nlm.nih.gov/pubmed/20384362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900448f
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