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Precipitation-free high-affinity multivalent binding by inline lectin ligands
Multivalent ligand–protein interactions are a key concept in biology mediating, for example, signalling and adhesion. Multivalent ligands often have tremendously increased binding affinities. However, they also can cause crosslinking of receptor molecules leading to precipitation of ligand–receptor...
Guardat en:
| Publicat a: | Chem Sci |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Royal Society of Chemistry
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8159369/ https://ncbi.nlm.nih.gov/pubmed/34122979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc01744b |
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