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Precipitation-free high-affinity multivalent binding by inline lectin ligands
Multivalent ligand–protein interactions are a key concept in biology mediating, for example, signalling and adhesion. Multivalent ligands often have tremendously increased binding affinities. However, they also can cause crosslinking of receptor molecules leading to precipitation of ligand–receptor...
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| Publicado en: | Chem Sci |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Royal Society of Chemistry
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8159369/ https://ncbi.nlm.nih.gov/pubmed/34122979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc01744b |
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