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Influence of multivalent nitrilotriacetic acid lipid-ligand affinity on the circulation half-life in mice of a liposome-attached his(6)-protein
Metal chelation-ligand interactions, such as occur between nitrilotriacetic acid (NTA)-nickel and multihistidines, enable the non-covalent attachment of histidine-modified proteins to liposomes and other particles. We compared three lipids: a mono-NTA lipid (circa 10 uM affinity) and two tris-NTA li...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874083/ https://ncbi.nlm.nih.gov/pubmed/20384362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900448f |
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