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Mechanism of pH-Triggered Collapse of Phosphatidylethanolamine Liposomes Stabilized by an Ortho Ester Polyethyleneglycol Lipid

The mechanism of pH-triggered destabilization of liposomes composed of a polyethyleneglycol-orthoester-distearoylglycerol lipid (POD) and phosphatidyl ethanolamine (PE) has been studied using an ANTS/DPX leakage and a lipid-mixing assay. We developed a kinetic model that relates POD hydrolysis to li...

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Detalles Bibliográficos
Main Authors: Guo, Xin, MacKay, J. Andrew, Szoka, Francis C.
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302747/
https://ncbi.nlm.nih.gov/pubmed/12609880
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