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Novel pH-Sensitive Cationic Lipids with Linear Ortho Ester Linkers for Gene Delivery
In an effort to develop pH-sensitive lipoplexes for efficient gene delivery, we report three novel cationic lipids containing a linear ortho ester linker that conjugates either the headgroup (Type I) or one hydrocarbon chain (Type II) with the rest of the lipid molecule. The cationic lipids carry ei...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383799/ https://ncbi.nlm.nih.gov/pubmed/22480493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2012.03.013 |
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