Involvement of Noradrenergic Transmission in the PVN on CREB Activation, TORC1 Levels, and Pituitary-Adrenal Axis Activity during Morphine Withdrawal

Experimental and clinical findings have shown that administration of adrenoceptor antagonists alleviated different aspects of drug withdrawal and dependence. The present study tested the hypothesis that changes in CREB activation and phosphorylated TORC1 levels in the hypothalamic paraventricular nu...

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Главные авторы: Martín, Fátima, Núñez, Cristina, Marín, M. Teresa, Laorden, M. Luisa, Kovács, Krisztina J., Milanés, M. Victoria
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280277/
https://ncbi.nlm.nih.gov/pubmed/22355339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031119
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