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CRF(2) mediates the increased noradrenergic activity in the hypothalamic paraventricular nucleus and the negative state of morphine withdrawal in rats

BACKGROUND AND PURPOSE: Recent evidence suggests that corticotropin-releasing factor (CRF) receptor signalling is involved in modulating the negative symptoms of opiate withdrawal. In this study, a series of experiments were performed to further characterize the role of CRF-type 2 receptor (CRF(2))...

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Autors principals: Navarro-Zaragoza, Javier, Núñez, Cristina, Ruiz-Medina, Jessica, Laorden, M Luisa, Valverde, Olga, Milanés, M Victoria
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042196/
https://ncbi.nlm.nih.gov/pubmed/20973778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01090.x
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