Glucocorticoid receptors participate in the opiate withdrawal-induced stimulation of rats NTS noradrenergic activity and in the somatic signs of morphine withdrawal

BACKGROUND AND PURPOSE: Recent evidence suggests that glucocorticoid receptor (GR) is a major molecular substrate of addictive properties of drugs of abuse. Hence, we performed a series of experiments to further characterize the role of GR signalling in opiate withdrawal-induced physical signs of de...

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Autors principals: Navarro-Zaragoza, Javier, Hidalgo, Juana M, Laorden, M Luisa, Milanés, M Victoria
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2012
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402777/
https://ncbi.nlm.nih.gov/pubmed/22364199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01918.x
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