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Germinal center B cell and T follicular helper cell development initiates in the inter-follicular zone

We identify the interfollicular (IF) zone as the site where germinal center B cell and T follicular helper (Tfh) cell differentiation initiates. For the first two days post-immunization, antigen-specific T and B cells remained confined within the IF zone, formed long-lived interactions, and upregula...

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Hlavní autoři: Kerfoot, Steven M., Yaari, Gur, Patel, Jaymin R., Johnson, Kody L., Gonzalez, David G., Kleinstein, Steven H., Haberman, Ann M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280079/
https://ncbi.nlm.nih.gov/pubmed/21636295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.03.024
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