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Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes

Ubiquitin and UBL (ubiquitin-like) modifiers are small proteins that covalently modify other proteins to alter their properties or behaviours. Ubiquitin modification (ubiquitylation) targets many substrates, often leading to their proteasomal degradation. NEDD8 (neural-precursor-cell-expressed devel...

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Detalhes bibliográficos
Main Authors: Hjerpe, Roland, Thomas, Yann, Chen, Jesse, Zemla, Aleksandra, Curran, Siobhan, Shpiro, Natalia, Dick, Lawrence R., Kurz, Thimo
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280039/
https://ncbi.nlm.nih.gov/pubmed/22004789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111671
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