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Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1

NEDD8 (neural precursor cell expressed developmentally downregulated gene 8)-specific protease NEDP1 processes preNEDD8 to its mature form and deconjugates NEDD8 from substrates such as p53 and cullins. Although NEDD8 and ubiquitin are highly related in sequence and structure, their attachment to a...

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Detalhes bibliográficos
Main Authors: Shen, Lin-nan, Liu, Huanting, Dong, Changjiang, Xirodimas, Dimitris, Naismith, James H, Hay, Ronald T
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142549/
https://ncbi.nlm.nih.gov/pubmed/15775960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600628
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