Hypoxia-Inducible Transcription Factors Stabilization in the Thick Ascending Limb Protects against Ischemic Acute Kidney Injury

Hypoxia-inducible transcription factors (HIF) protect cells against oxygen deprivation, and HIF stabilization before ischemia mitigates tissue injury. Because ischemic acute kidney injury (AKI) often involves the thick ascending limb (TAL), modulation of HIF in this segment may be protective. Here,...

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Detalhes bibliográficos
Main Authors: Schley, Gunnar, Klanke, Bernd, Schödel, Johannes, Forstreuter, Frauke, Shukla, Deepa, Kurtz, Armin, Amann, Kerstin, Wiesener, Michael S., Rosen, Seymour, Eckardt, Kai-Uwe, Maxwell, Patrick H., Willam, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279994/
https://ncbi.nlm.nih.gov/pubmed/21921145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010121249
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