Hypoxia-Inducible Transcription Factors Stabilization in the Thick Ascending Limb Protects against Ischemic Acute Kidney Injury

Hypoxia-inducible transcription factors (HIF) protect cells against oxygen deprivation, and HIF stabilization before ischemia mitigates tissue injury. Because ischemic acute kidney injury (AKI) often involves the thick ascending limb (TAL), modulation of HIF in this segment may be protective. Here,...

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Detaylı Bibliyografya
Asıl Yazarlar: Schley, Gunnar, Klanke, Bernd, Schödel, Johannes, Forstreuter, Frauke, Shukla, Deepa, Kurtz, Armin, Amann, Kerstin, Wiesener, Michael S., Rosen, Seymour, Eckardt, Kai-Uwe, Maxwell, Patrick H., Willam, Carsten
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2011
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279994/
https://ncbi.nlm.nih.gov/pubmed/21921145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010121249
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