HIF-Prolyl Hydroxylases in the Rat Kidney : Physiologic Expression Patterns and Regulation in Acute Kidney Injury

Hypoxia-inducible transcription factors (HIFs) play important roles in the response of the kidney to systemic and regional hypoxia. Degradation of HIFs is mediated by three oxygen-dependent HIF-prolyl hydroxylases (PHDs), which have partially overlapping characteristics. Although PHD inhibitors, whi...

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Detalhes bibliográficos
Main Authors: Schödel, Johannes, Klanke, Bernd, Weidemann, Alexander, Buchholz, Björn, Bernhardt, Wanja, Bertog, Marko, Amann, Kerstin, Korbmacher, Christoph, Wiesener, Michael, Warnecke, Christina, Kurtz, Armin, Eckardt, Kai-Uwe, Willam, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671255/
https://ncbi.nlm.nih.gov/pubmed/19349364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080687
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