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Inhibition of Prolyl Hydroxylases Increases Erythropoietin Production in ESRD
The reasons for inadequate production of erythropoietin (EPO) in patients with ESRD are poorly understood. A better understanding of EPO regulation, namely oxygen-dependent hydroxylation of the hypoxia-inducible transcription factor (HIF), may enable targeted pharmacological intervention. Here, we t...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Nephrology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014028/ https://ncbi.nlm.nih.gov/pubmed/21115615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010010116 |
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