Mast Cells Mediate Acute Kidney Injury through the Production of TNF

Leukocyte recruitment contributes to acute kidney injury (AKI), but the mechanisms by which leukocytes promote injury are not completely understood. The degranulation of mast cells releases inflammatory molecules, including TNF, but whether these cells participate in the pathogenesis of AKI is unkno...

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Main Authors: Summers, Shaun A., Chan, Jacky, Gan, Poh-Yi, Dewage, Lakshi, Nozaki, Yuji, Steinmetz, Oliver M., Nikolic-Paterson, David J., Kitching, A. Richard, Holdsworth, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2011
Assuntos:
Basic Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279934/
https://ncbi.nlm.nih.gov/pubmed/22021718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011020182
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