Mast Cells Contribute to Peripheral Tolerance and Attenuate Autoimmune Vasculitis

Mast cells contribute to the modulation of the immune response, but their role in autoimmune renal disease is not well understood. Here, we induced autoimmunity resulting in focal necrotizing GN by immunizing wild-type or mast cell-deficient (Kit(W-sh/W-sh)) mice with myeloperoxidase. Mast cell-defi...

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Main Authors: Gan, Poh-Yi, Summers, Shaun A., Ooi, Joshua D., O’Sullivan, Kim M., Tan, Diana S.Y., Muljadi, Ruth C.M., Odobasic, Dragana, Kitching, A. Richard, Holdsworth, Stephen R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2012
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507370/
https://ncbi.nlm.nih.gov/pubmed/23138486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012060572
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