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The C3aR promotes macrophage infiltration and regulates ANCA production but does not affect glomerular injury in experimental anti-myeloperoxidase glomerulonephritis

The anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitides are autoimmune diseases associated with significant morbidity and mortality. They often affect the kidney causing rapidly progressive glomerulonephritis. While signalling by complement anaphylatoxin C5a though the C5a receptor i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dick, Jonathan, Gan, Poh-Yi, Kitching, A. Richard, Holdsworth, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760037/
https://ncbi.nlm.nih.gov/pubmed/29315316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190655
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