Mast Cells Mediate Acute Kidney Injury through the Production of TNF

Leukocyte recruitment contributes to acute kidney injury (AKI), but the mechanisms by which leukocytes promote injury are not completely understood. The degranulation of mast cells releases inflammatory molecules, including TNF, but whether these cells participate in the pathogenesis of AKI is unkno...

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Bibliografiske detaljer
Main Authors: Summers, Shaun A., Chan, Jacky, Gan, Poh-Yi, Dewage, Lakshi, Nozaki, Yuji, Steinmetz, Oliver M., Nikolic-Paterson, David J., Kitching, A. Richard, Holdsworth, Stephen R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2011
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279934/
https://ncbi.nlm.nih.gov/pubmed/22021718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011020182
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