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C-Terminal Fluorescent Labeling Impairs Functionality of DNA Mismatch Repair Proteins
The human DNA mismatch repair (MMR) process is crucial to maintain the integrity of the genome and requires many different proteins which interact perfectly and coordinated. Germline mutations in MMR genes are responsible for the development of the hereditary form of colorectal cancer called Lynch s...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3279419/ https://ncbi.nlm.nih.gov/pubmed/22348133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031863 |
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