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C-Terminal Fluorescent Labeling Impairs Functionality of DNA Mismatch Repair Proteins

The human DNA mismatch repair (MMR) process is crucial to maintain the integrity of the genome and requires many different proteins which interact perfectly and coordinated. Germline mutations in MMR genes are responsible for the development of the hereditary form of colorectal cancer called Lynch s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Brieger, Angela, Plotz, Guido, Hinrichsen, Inga, Passmann, Sandra, Adam, Ronja, Zeuzem, Stefan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279419/
https://ncbi.nlm.nih.gov/pubmed/22348133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031863
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