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Shortened β-cell lifespan leads to β-cell deficit in a rodent model of type 2 diabetes
Since the fundamental defect in both type 1 and type 2 diabetes is β-cell failure, there is increasing interest in the capacity, if any, for β-cell regeneration. Insights into typical β-cell age and lifespan during normal development and how these are influenced in diabetes is desirable to realistic...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3279301/ https://ncbi.nlm.nih.gov/pubmed/21343541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00504.2010 |
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