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Development of factors to convert frequency to rate for β-cell replication and apoptosis quantified by time-lapse video microscopy and immunohistochemistry

An obstacle to development of methods to quantify β-cell turnover from pancreas tissue is the lack of conversion factors for the frequency of β-cell replication or apoptosis detected by immunohistochemistry to rates of replication or apoptosis. We addressed this obstacle in islets from 1-mo-old rats...

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Detalhes bibliográficos
Main Authors: Saisho, Yoshifumi, Manesso, Erica, Gurlo, Tatyana, Huang, Chang-jiang, Toffolo, Gianna M., Cobelli, Claudio, Butler, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043232/
https://ncbi.nlm.nih.gov/pubmed/18940937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90697.2008
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