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Shortened β-cell lifespan leads to β-cell deficit in a rodent model of type 2 diabetes

Since the fundamental defect in both type 1 and type 2 diabetes is β-cell failure, there is increasing interest in the capacity, if any, for β-cell regeneration. Insights into typical β-cell age and lifespan during normal development and how these are influenced in diabetes is desirable to realistic...

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Detaylı Bibliyografya
Asıl Yazarlar: Manesso, Erica, Toffolo, Gianna M., Butler, Alexandra E., Butler, Peter C., Cobelli, Claudio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279301/
https://ncbi.nlm.nih.gov/pubmed/21343541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00504.2010
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