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Use of Cre-adenovirus and CAR transgenic mice for efficient deletion of genes in post-thymic T cells
Conditional gene deletion using lineage-specific transgenic expression of Cre has been useful for defining the role of specific gene products in mice in vivo. However, this technology has had limitations for studies of peripheral T cell biology, since the T-lineage promoters commonly used are active...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278801/ https://ncbi.nlm.nih.gov/pubmed/18177887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2007.11.013 |
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