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Fluoride ion catalyzed alkylation of nucleic acid derivatives using trialkyl phosphates, dialkyl sulfates and alkyl methanesulfonates.

Trimethyl phosphate, dimethyl and diethyl sulfate and methyl and ethyl methanesulfonate all give high yields of alkylation on purines and pyrimidines in the presence of tetrabutylammonium fluoride. Trimethyl phosphate produces near quantitative yields of diesters of nucleic acids but gives virtually...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Ogilvie, K K, Beaucage, S L, Gillen, M F, Entwistle, D W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 1979
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327849/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/223127/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/6.6.2261
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