Fluoride ion catalyzed alkylation of nucleic acid derivatives using trialkyl phosphates, dialkyl sulfates and alkyl methanesulfonates.

Trimethyl phosphate, dimethyl and diethyl sulfate and methyl and ethyl methanesulfonate all give high yields of alkylation on purines and pyrimidines in the presence of tetrabutylammonium fluoride. Trimethyl phosphate produces near quantitative yields of diesters of nucleic acids but gives virtually...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Ogilvie, K K, Beaucage, S L, Gillen, M F, Entwistle, D W
Format: Artigo
Sprog:Inglês
Udgivet: 1979
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC327849/
https://ncbi.nlm.nih.gov/pubmed/223127
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker