Differential Regulation of Adhesion Complex Turnover by ROCK1 and ROCK2

BACKGROUND: ROCK1 and ROCK2 are serine/threonine kinases that function downstream of the small GTP-binding protein RhoA. Rho signalling via ROCK regulates a number of cellular functions including organisation of the actin cytoskeleton, cell adhesion and cell migration. METHODOLOGY/PRINCIPAL FINDINGS...

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Detalhes bibliográficos
Main Authors: Lock, Frances E., Ryan, Katie R., Poulter, Natalie S., Parsons, Maddy, Hotchin, Neil A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278444/
https://ncbi.nlm.nih.gov/pubmed/22348083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031423
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