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Molecular basis for interaction of let-7 microRNAs with Lin28

MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression. Among these, members of the let-7 miRNA family control many cell fate determination genes to influence pluripotency, differentiation, and transformation. Lin28 is a specific, post-transcriptional inhibitor of let-7...

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Bibliografiske detaljer
Main Authors: Nam, Yunsun, Chen, Casandra, Gregory, Richard I, Chou, James J, Sliz, Piotr
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277843/
https://ncbi.nlm.nih.gov/pubmed/22078496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.10.020
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