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Cathepsin B-sensitive polymers for compartment-specific degradation and nucleic acid release
Degradable cationic polymers are desirable for in vivo nucleic acid delivery because they offer significantly decreased toxicity over non-degradable counterparts. Peptide linkers provide chemical stability and high specificity for particular endopeptidases but have not been extensively studied for n...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277802/ https://ncbi.nlm.nih.gov/pubmed/22036879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.10.016 |
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