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Development of switchable polymers to address the dilemma of stability and cargo release in polycationic nucleic acid carriers

Cationic polymer gene delivery vehicles that effectively resist premature serum degradation often have difficulty releasing their nucleic acid cargoes. In this work, we report a pH-sensitive polymer (SP), poly(oligo(ethylene glycol) monomethyl ether methacrylate)-co-poly(2-(dimethylamino)ethyl metha...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Cheng, Yilong, Sellers, Drew L., Tan, James-Kevin Y., Peeler, David J., Horner, Philip J., Pun, Suzie H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382035/
https://ncbi.nlm.nih.gov/pubmed/28284104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.02.036
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