Reducible HPMA-co-oligolysine copolymers for nucleic acid delivery

Biodegradability can be incorporated into cationic polymers via use of disulfide linkages that are degraded in the reducing environment of the cell cytosol. In this work, N-(2-hydroxypropyl)methacrylamide (HPMA) and methacrylamido-functionalized oligo-L-lysine peptide monomers with either a non-redu...

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Bibliografische gegevens
Hoofdauteurs: Shi, Julie, Johnson, Russell N., Schellinger, Joan G., Carlson, Peter M., Pun, Suzie H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240689/
https://ncbi.nlm.nih.gov/pubmed/21893178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2011.08.015
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