Reducible HPMA-co-oligolysine copolymers for nucleic acid delivery

Biodegradability can be incorporated into cationic polymers via use of disulfide linkages that are degraded in the reducing environment of the cell cytosol. In this work, N-(2-hydroxypropyl)methacrylamide (HPMA) and methacrylamido-functionalized oligo-L-lysine peptide monomers with either a non-redu...

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Bibliografiske detaljer
Main Authors: Shi, Julie, Johnson, Russell N., Schellinger, Joan G., Carlson, Peter M., Pun, Suzie H.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240689/
https://ncbi.nlm.nih.gov/pubmed/21893178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2011.08.015
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