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Reducible HPMA-co-oligolysine copolymers for nucleic acid delivery
Biodegradability can be incorporated into cationic polymers via use of disulfide linkages that are degraded in the reducing environment of the cell cytosol. In this work, N-(2-hydroxypropyl)methacrylamide (HPMA) and methacrylamido-functionalized oligo-L-lysine peptide monomers with either a non-redu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3240689/ https://ncbi.nlm.nih.gov/pubmed/21893178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2011.08.015 |
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