Melittin-grafted HPMA-Oligolysine Based Copolymers for Improved Gene Delivery

Non-viral gene delivery systems capable of transfecting cells in the brain are critical in realizing the potential impact of nucleic acid therapeutics for diseases of the central nervous system. In this study, the membrane-lytic peptide melittin was incorporated into block copolymers synthesized by...

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Detalhes bibliográficos
Main Authors: Schellinger, Joan G., Pahang, Joshuel A., Johnson, Russell N., Chu, David S.H., Sellers, Drew L., Maris, Don O., Convertine, Anthony J., Stayton, Patrick S., Horner, Philip J., Pun, Suzie H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552146/
https://ncbi.nlm.nih.gov/pubmed/23261217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.09.072
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