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Phase I trial of ATRA-IV and depakote in patients with advanced solid tumor malignancies
Retinoic acid derivatives have shown their greatest benefit in acute promyelocytic leukemia, but have also demonstrated pre-clinical anti-cancer effects in some solid tumors. Histone deacetylase inhibitors, by upregulating gene expression, are able to limit cancer cell proliferation and induce apopt...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277777/ https://ncbi.nlm.nih.gov/pubmed/20200483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.9.9.11436 |
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