Phase I trial outcomes in older patients with advanced solid tumours

BACKGROUND: This study had two aims: (a) to test the hypothesis that advanced age is associated with lower levels of tolerability and clinical benefit to experimental Phase I trial agents; (b) to assess the validity of the Royal Marsden Hospital (RMH) prognostic score as a patient selection tool in...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Khan, K H, Yap, T A, Ring, A, Molife, L R, Bodla, S, Thomas, K, Zivi, A, Smith, A, Judson, I, Banerji, U, de Bono, J S, Kaye, S B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742590/
https://ncbi.nlm.nih.gov/pubmed/26757260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.477
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