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A phase I study of intravenous and oral rucaparib in combination with chemotherapy in patients with advanced solid tumours
BACKGROUND: This study evaluated safety, pharmacokinetics, and clinical activity of intravenous and oral rucaparib, a poly(ADP-ribose) polymerase inhibitor, combined with chemotherapy in patients with advanced solid tumours. METHODS: Initially, patients received escalating doses of intravenous rucap...
שמור ב:
| הוצא לאור ב: | Br J Cancer |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5379148/ https://ncbi.nlm.nih.gov/pubmed/28222073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.36 |
| תגים: |
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