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Genetic background effects on age-related hearing loss associated with Cdh23 variants in mice
Inbred strain variants of the Cdh23 gene have been shown to influence the onset and progression of age-related hearing loss (AHL) in mice. In linkage backcrosses, the recessive Cdh23 allele (ahl) of the C57BL/6J strain, when homozygous, confers increased susceptibility to AHL, while the dominant all...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277672/ https://ncbi.nlm.nih.gov/pubmed/22138310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2011.11.007 |
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